Cosmos SDK for App-Chains
Verdict: The definitive choice for sovereign, purpose-built chains.
Strengths: The Cosmos SDK provides a modular, battle-tested framework for launching a blockchain with full sovereignty. You control your own validator set, governance, and fee economics. Native interoperability via IBC allows your chain to connect to a vast ecosystem (e.g., Osmosis, Injective, Celestia). The framework's flexibility supports custom virtual machines (CosmWasm) and consensus layers (CometBFT).
Trade-offs: You are responsible for bootstrapping security and liquidity. Development complexity is higher than deploying a smart contract.
Solana SDK for App-Chains
Verdict: Not applicable; use Solana as a monolithic L1.
Context: Solana is a single, high-performance blockchain. The "Solana SDK" (primarily the solana CLI and anchor framework) is for building programs (smart contracts) on the Solana network, not for launching independent chains. For teams wanting Solana's performance without its congestion, consider a Solana Virtual Machine (SVM) L2 like Eclipse or Nitrocloud.